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If you forget a dose of levothyroxinetake the missed dose as soon as you remember itIf it is almost time for your next doseskip the missed doseDo not take a double dose of this medication.

Circulating thyroid hormones are greater than 99bound to plasma proteinsincluding thyroxine-binding globulinTBGthyroxine-binding prealbuminTBPAand albuminTBAwhose capacities and affinities vary for each hormoneThe higher affinity of both TBG and TBPA for T 4 partially explains the higher serum levelsslower metabolic clearanceand longer half-life of T 4 compared to T 3Protein-bound thyroid hormones exist in reverse equilibrium with small amounts of free hormoneOnly unbound hormone is metabolically activeMany drugs and physiologic conditions affect the binding of thyroid hormones to serum proteinssee PRECAUTIONSDrug Interactions and Drug-Laboratory Test InteractionsThyroid hormones do not readily cross the placental barriersee PRECAUTIONSPregnancy

Tell your doctor about all medications you usestart usingor stop using during your treatment with levothyroxineThis includes prescriptionover-the-countervitaminand herbal productsGive a list of all your medicines to any healthcare provider who treats you.

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because levothyroxine is the generic alternative for levothroid, levoxyl, synthroid and unithroid, there is no manufacturer-sponsored prescription assistance program for levothyroxine 125 mcg.

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